RESULTS & PUBLICATIONS:
Articles:
Bousset L, Pieri L, Ruiz-Arlandis G, Gath J, Jensen PH, Habenstein B, Madiona K, Olieric V, Böckmann A, Meier BH, Melki R.
Structural and functional characterization of two alpha-synuclein strains
Nat Communications. 2013;4:2575 download
Fieblinger T, Sebastianutto I, Alcacer C, Bimpisidis Z, Maslava N, Sandberg S, Engblom D, Cenci MA.
Mechanisms of Dopamine D1 Receptor-Mediated ERK1/2 Activation in the Parkinsonian Striatum and Their Modulation by Metabotropic Glutamate Receptor Type 5
J Neurosci. 2014 Mar 26;34(13):4728-40 download
Lin F, Ghislat G, Luo S, Renna M, Siddiqi F, Rubinsztein DC.
XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation.
Hum Mol Genet. 2015 May 15;24(10):2899-913 download
Monsellier E, Redeker V, Ruiz-Arlandis G, Bousset L, Melki R.
Molecular Interaction between the Chaperone Hsc70 and the N-terminal Flank of Huntingtin Exon 1 Modulates Aggregation
J Biol Chem. 2015 Jan 30;290(5):2560-76. download
Massai L, Petricca L, Magnoni L, Rovetini L, Haider S, Andre R, Tabrizi SJ, Süssmuth SD, Landwehrmeyer BG, Caricasole A, Pollio G, Bernocco S.
Development of an ELISA assay for the quantification of soluble huntingtin in human blood cells
BMC Biochem. 2013 Nov 25;14:34. download
Fodale V, Kegulian NC, Verani M, Cariulo C, Azzollini L, Petricca L, Daldin M, Boggio R, Padova A, Kuhn R, Pacifici R, Macdonald D, Schoenfeld RC, Park H, Isas JM, Langen R, Weiss A, Caricasole A
Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy.
PLoS One. 2014 Dec 2;9(12):e112262. download
Weber JJ, Sowa AS, Binder T, Hübener J.
From Pathways to Targets: Understanding the Mechanisms behind Polyglutamine Disease
Biomed Res Int. 2014;2014:701758 download
Book chapter:
M Pavel and DC Rubinsztein.
Autophagy upregulation as a therapeutic strategy for neurodegenerative diseases.
In: Antitumor Potential and other Emerging Medicinal Properties of Natural Compunds.
Springer. Eds. EF Fang and TB Ng (2013, pp 227-238)